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UIC researcher finds potential new way to treat chronic migraine

UIC researcher finds potential new way to treat chronic migraine By discovering a potential new cellular mechanism for migraines, researchers may have also found a new way to treat chronic migraine. Amynah Pradhan, associate professor of psychiatry at the University of Illinois Chicago, is the senior author of the study, whose goal was to identify a new mechanism of chronic migraine, and propose a cellular pathway for migraine therapies. The study, Neuronal complexity is attenuated in preclinical models of migraine and restored by HDAC6 inhibition, is published in eLife. Pradhan, whose research focus is on the neurobiology of pain and headache, explained that the dynamic process of routing and rerouting connections among nerve cells, called neural plasticity, is critical to both the causes and cures for disorders of the central nervous system such as depression, chronic pain, and addiction.

New mutation raises risk for AFib, heart failure for people of color

Credit: UIC/Jenny Fontaine A new mutation found in a gene associated with an increased risk of atrial fibrillation poses a significantly increased risk for heart failure in Black people. The discovery, made by researchers at the University of Illinois Chicago, could change current guidelines that recommend against genetic testing in people with atrial fibrillations, also known as AFib. We found that this new variant confers a significantly increased risk in African Americans, and this mutation has a 50% chance of being passed on to offspring, said Dr. Dawood Darbar, UIC professor of medicine and pharmacology at the College of Medicine. Since it increases risk for heart failure, it would be wise to test people with atrial fibrillation to see if they carry this dangerous gene.

Featured Evanstonian: Sandy Chen

340B hospitals offer more assistance removing barriers to medication access

University of Illinois at Chicago According to a new study published in the journal Research in Social and Administrative Pharmacy, hospitals that participate in the 340B Drug Pricing Program provide more medication access services which are services that help remove barriers to accessing necessary medications than comparably sized non-340B hospitals. The University of Illinois Chicago researchers who conducted the study, which included a survey of available services sent to a nationally representative sample of hospitals across the U.S., suggest that 340B participating hospitals may be better positioned to create and administer programs that support patients who are uninsured or underinsured and those who may have job, transportation and other social insecurities.

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