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Researchers Invent New Gene Editing Tool

Researchers Invent New Gene Editing Tool March 3, 2021 Specially engineered guide RNA molecules called “proGuides” may allow scientists to program sequential gene edits over time. Researchers from the University of Illinois Chicago (UIC) have discovered a new gene editing technique that allows for the programming of sequential cuts or edits over time. The new process developed by UIC s Bradley Merrill, lead author of the paper published in Molecular Cell, involves using special molecules called guide RNA that ferry the Cas9 enzyme within the cell and determine the precise DNA sequence at which Cas9 will cut. They call their specially engineered guide RNA molecules proGuides, and the molecules allow for the programmed sequential editing of DNA using Cas9.

Lessons from Wuhan: What managers and employees need to know

 E-Mail As COVID-19 lockdowns and quarantines are lifted, businesses are now faced with the challenge of how to keep their employees who are returning to work motivated and engaged. A study led by a University of Illinois Chicago researcher shows that both employees and managers have an important part to play in promoting employee engagement during the pandemic. The research, published in the Journal of Applied Psychology, suggests employee engagement and performance are the highest when employees are mentally prepared for their return to work and their managers are strongly committed to employees health and safety at work. Given the turmoil and distress during lockdowns and quarantines, employees may have trouble reconnecting with their work. We wanted to find out what factors could help employees effectively stay engaged at work upon return. This is an important topic because highly engaged employees tend to intrinsically enjoy their work and outperform others, says le

Illinois Capital Development Board announces plans

Illinois Capital Development Board announces plans
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Illinois Capital Development Board Announces plans for the Design and Construction of the University of Illinois New Computer Design, Research and Learning Center

Illinois Capital Development Board Announces plans for the Design and Construction of the University of Illinois New Computer Design, Research and Learning Center
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New 4D Hydrogels can Change Shape in Response to Stimuli

New 4D Hydrogels can Change Shape in Response to Stimuli Written by AZoMMar 2 2021 For a long time, tissue engineering has relied on geometrically static scaffolds that are seeded with cells in the laboratory to make new tissues and even organs. 4D hydrogel-based materials can undergo multiple conformational shape changes in response to environmental cues. Image Credit: Aixiang Ding. Generally, the scaffolding material is a biodegradable polymer structure that is provided with cells, and if the cells are supplied with proper nutrients, then they develop into a tissue as the basic scaffold biodegrades. However, this model disregards the exceptionally dynamic morphological processes that form the basis of the natural growth of tissues.

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