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CRISPR technology to cure sickle cell disease at UIC

 E-Mail University of Illinois Chicago is one of the U.S. sites participating in clinical trials to cure severe red blood congenital diseases such as sickle cell anemia or Thalassemia by safely modifying the DNA of patients blood cells. The first cases treated with this approach were recently published in an article co-authored by Dr. Damiano Rondelli, the Michael Reese Professor of Hematology at the UIC College of Medicine. The article reports two patients have been cured of beta thalassemia and sickle cell disease after their own genes were edited with CRISPR-Cas9 technology. The two researchers who invented this technology received the Nobel Prize in Chemistry in 2020.

Genomic test has lower prognostic accuracy in minority patients with breast cancer

Genomic test has lower prognostic accuracy in minority patients with breast cancer Black women have higher recurrence and mortality rates than non-Hispanic white women for certain types of breast cancer, according to a University of Illinois Chicago researcher s study published recently in JAMA Oncology. Dr. Kent Hoskins, associate professor in the UIC College of Medicine s division of hematology/oncology, and co-leader of the Breast Cancer Research group in the University of Illinois Cancer Center, published the study, Association of race/ethnicity and the 21-gene Recurrence Score with breast cancer-specific mortality among US women in the Jan. 21 online issue. Hoskins and the research team sought to discover if breast cancer-specific mortality among women with estrogen receptor-positive, axillary node-negative breast cancer differs by race within risk categories defined by the Oncotype Recurrence Score, or RS, which is a genomic test that analyzes the activity of a group of

U of I trustees freeze undergrad tuition rates for 2021

Canton Daily Ledger The University of Illinois Board of Trustees Thursday voted to freeze tuition for incoming in-state freshmen and non-resident undergraduates for the 2021-22 academic year. Trustees also approved modest increases in the cost of room and board: 2% at the University of Illinois Urbana-Champaign, 2.6% at the University of Illinois Chicago and 1.4% at the University of Illinois Springfield. Small increases in fees, set in consultation with students, were approved for Urbana-Champaign and Chicago. Trustees met virtually due to the COVID-19 pandemic. The U of I System has now frozen tuition rates for in-state undergraduate students in six of the past seven years, part of an ongoing commitment to containing costs for students and their families, system President Tim Killeen said. Tuition rates for in-state undergraduate students were frozen from 2015-19. During the 2020-21 academic year, system leadership decided because of the pandemic to cover the costs of a 1.8 per

Study finds racial disparities in breast cancer prognosis testing

 E-Mail Black women have higher recurrence and mortality rates than non-Hispanic white women for certain types of breast cancer, according to a University of Illinois Chicago researcher s study published recently in JAMA Oncology. Dr. Kent Hoskins, associate professor in the UIC College of Medicine s division of hematology/oncology, and co-leader of the Breast Cancer Research group in the University of Illinois Cancer Center, published the study, Association of race/ethnicity and the 21-gene Recurrence Score with breast cancer-specific mortality among US women in the Jan. 21 online issue. Hoskins and the research team sought to discover if breast cancer-specific mortality among women with estrogen receptor-positive, axillary node-negative breast cancer differs by race within risk categories defined by the Oncotype Recurrence Score, or RS, which is a genomic test that analyzes the activity of a group of genes that can affect how a cancer is likely to behave and respond to tre

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