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 E-Mail IMAGE: Shown here in green are branches, or axons, from cells in the substantia nigra region that connect to the midbrain. Red spots label where cells connect. view more  Credit: Lauren McElvain / Kleinfeld lab / UC San Diego) Thousands of our daily activities, from making coffee to taking a walk to saying hello to a neighbor, are made possible through an ancient collection of brain structures tucked away near the center of the cranium. The cluster of neurons known as the basal ganglia is a central hub for regulating a vast array of routine motor and behavior functions. But when signaling in the basal ganglia is weakened or broken, debilitating movement and psychiatric disorders can emerge, including Parkinson s disease, Tourette s syndrome, attention deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder.

United statesYuncong chenJohnj ngaiBrenda bloodgoodLauren mcelvainG stefano brigidiNeurophysics laboratory of professor david kleinfeldNational institutes of healthZuckerman institute principal investigator rui costaBrain researchDivision of biological sciences section neurobiologyColumbia vagelos college of physiciansUniversity of utah school medicineUniversity of california san diegoTourette association of americaDivision of physical sciences department physics