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Research shows cytonemes distribute Wnt proteins in vertebrate tissue
Scientists have made a pivotal breakthrough in understanding the way in which cells communicate with each other.
A team of international researchers, including experts from the University of Exeter’s Living Systems Institute, has identified how signalling pathways of Wnt proteins - which orchestrate and control many cell developmental processes – operate on both molecular and cellular levels.
Various mechanisms exist for cells to communicate with each other, and many are essential for development. This information exchange between cells is often based on signalling proteins that activate specific intracellular signalling cascades to control cell behaviour at a distance.
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Scientists have developed a pioneering new technique that could revolutionise the accuracy, precision and clarity of super-resolution imaging systems.
A team of scientists, led by Dr Christian Soeller from the University of Exeter s Living Systems Institute, which champions interdisciplinary research and is a hub for new high-resolution measurement techniques, has developed a new way to improve the very fine, molecular imaging of biological samples.
The new method builds upon the success of an existing super-resolution imaging technique called DNA-PAINT (Point Accumulation for Imaging in Nanoscale Topography) - where molecules in a cell are labelled with marker molecules that are attached to single DNA strands.