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Coronavirus vaccines may not work in some people. It’s because of their underlying conditions. Ariana Eunjung Cha “Risk is very different for people in my situation,” said Maria Hoffman, a kidney transplant patient who works for the Medical University of South Carolina. (Brett Lemmo for The Washington Post) Maria Hoffman feels as though she has been left behind. Her adopted hometown of Charleston, S.C., is hopping with restaurants and bars fully open, park concerts in full swing and maskless friends reuniting with hugs on streets. Hoffman, 39, is fully vaccinated and eager to rejoin the world. But as a kidney transplant patient, she is hesitant to participate for fear of becoming infected. “Risk is very different for people in my situation,” she said. “I am 100 percent acting like I am not immunized.”

New yorkUnited statesWhite houseDistrict of columbiaSan franciscoAmanda voisardBrett lemmoSarah farahAnthonys fauciMonica gandhiSeville christianRochelle walenskyMaria hoffmanCenters for diseaseUniversity of pittsburgh medical centerJohns hopkins university school of medicine