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10 Dec 2020
The pushback against Democrat Governor Gavin Newsom’s strict coronavirus lockdown is growing, including in rural communities where businesses and their customers are openly defying the orders.
That includes at Steve’s Sportsmans Cafe in Mariposa County, located in the foothills of the Sierra Nevada mountain range. Owner Steve Knauf is still serving up chicken fried steak and beef ribs to hungry crowds and said he is no longer listening to state and other officials.
“I think they’re trying to instill fear for something that’s not there,” Knauf said.
“My customers don’t want me to shut down, and I’m not going to,” said Robbie Nelson, owner of the Airport Inn Bar and Grill where people gathered for the comfort food.
Every day, hundreds of thousands if not millions of molecular reactions are happening in laboratories worldwide. Small droplets of liquid that give us a lens into an individual’s respiratory pathways are analyzed for whether or not they contain the pathogen of the year: SARS-CoV-2, the virus that causes Covid-19. The technique used for this analysis is called polymerase chain reaction (PCR), and it exploits the ability of genetic material to replicate. Although imperfect, it’s been critical in diagnosing the disease by amplifying genes specific to SARS-CoV-2. When it’s accurate, PCR helps confirm positive cases, slows the spread of infection, and allows health officials to treat individuals who have Covid-19.
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In January, when the escalation of novel coronavirus infections was still just beginning in China, immunologist Michel Nussenzweig realized that the world was facing an unusual situation and it was time for him to act. “It was clear that this would be a big problem because of the person-to-person transmission and the speed with which it was spreading,” says the researcher, who coordinates the Laboratory of Molecular Immunology at Rockefeller University in New York.
Over the following weeks, Nussenzweig and his team of 50 scientists temporarily put aside the research they had been working on. Instead, they began searching for antibodies (proteins synthesized by the immune system) in the blood of COVID-19 survivors that would be capable of neutralizing the novel coronavirus. To accomplish this, the researchers are counting on small donations of blood from 100 people who had the disease caused by the SARS-CoV-2 virus and were cured. As of the end of March, about 30 volunteers had a