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AI-designed serotonin sensor may help scientists study sleep, mental health

AI-designed serotonin sensor may help scientists study sleep, mental health ANI | Updated: Dec 25, 2020 10:33 IST Washington [US], December 25 (ANI): In an article in Cell, National Institutes of Health-funded researchers described how they used advanced genetic engineering techniques to transform a bacterial protein into a new research tool that may help monitor serotonin transmission with greater fidelity than current methods. Preclinical experiments, primarily in mice, showed that the sensor could detect subtle, real-time changes in brain serotonin levels during sleep, fear, and social interactions, as well as test the effectiveness of new psychoactive drugs. The study was funded, in part, by the NIH s Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative which aims to revolutionize our understanding of the brain under healthy and disease conditions.

Scientists develop AI-driven sensor to monitor brain serotonin levels in real time

Scientists develop AI-driven sensor to monitor brain serotonin levels in real time Share Via Email Scientists develop AI-driven sensor to monitor brain serotonin levels in real time Scientists have devised an artificial intelligence (AI)-designed sensor that can help monitor serotonin transmission in the brain under more natural conditions. This can help address sleep disorders and mental health in the future. Serotonin is a neurochemical that plays a critical role in the way the brain controls our thoughts and feelings. In an article in Cell, the US National Institutes of Health (NIH)-funded researchers described how they used advanced genetic engineering techniques to transform a bacterial protein into a new research tool that may help monitor serotonin transmission with greater fidelity than current methods.

New tool may help monitor serotonin transmission with greater fidelity than current methods

New tool may help monitor serotonin transmission with greater fidelity than current methods Serotonin is a neurochemical that plays a critical role in the way the brain controls our thoughts and feelings. For example, many antidepressants are designed to alter serotonin signals sent between neurons. In an article in Cell, National Institutes of Health-funded researchers described how they used advanced genetic engineering techniques to transform a bacterial protein into a new research tool that may help monitor serotonin transmission with greater fidelity than current methods. Preclinical experiments, primarily in mice, showed that the sensor could detect subtle, real-time changes in brain serotonin levels during sleep, fear, and social interactions, as well as test the effectiveness of new psychoactive drugs. The study was funded, in part, by the NIH s Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative which aims to revolutionize our understanding o

AI-designed serotonin sensor may help scientists study sleep and mental health

 E-Mail IMAGE: NIH BRAIN Initiative-funded scientists used artificial intelligence to help redesign a nutrient grabbing, Venus flytrap-shaped bacterial protein into a highly sensitive serotonin sensor. Here the sensor captured for the first. view more  Credit: Courtesy of Tian lab. University of California Davis School of Medicine. Serotonin is a neurochemical that plays a critical role in the way the brain controls our thoughts and feelings. For example, many antidepressants are designed to alter serotonin signals sent between neurons. In an article in Cell, National Institutes of Health-funded researchers described how they used advanced genetic engineering techniques to transform a bacterial protein into a new research tool that may help monitor serotonin transmission with greater fidelity than current methods. Preclinical experiments, primarily in mice, showed that the sensor could detect subtle, real-time changes in brain serotonin levels during sleep, fear, and so

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