Lutris Pharma Phase 1 Results of LUT014 for Skin Toxicities Associated with Treatment of Colorectal Cancer Patients with EGFR Inhibitors Published in Cancer Discovery prnewswire.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from prnewswire.com Daily Mail and Mail on Sunday newspapers.
Drug cocktail can effectively activate and expand muscle stem cells
Skeletal muscle – the type of muscle that attaches to bones and enables movement – is the most abundant tissue in the human body.
This tissue has the ability to regenerate after minor injuries, a process facilitated by resident muscle stem cells that help to build new muscle fibers. However, acute muscle loss (which can happen in severe accidents), progressive muscle loss, or genetic diseases, such as muscular dystrophy, may compromise this tissue repair process. In these cases, patients can experience mobility issues and have a reduced quality of life, underscoring the need for novel methods to help regenerate skeletal muscle.
email article
More than half of patients with steroid-refractory hand eczema responded quickly to a pan-Janus kinase (JAK) inhibitor in a randomized, placebo-controlled trial.
After 16 weeks of treatment, patients treated with the higher of two doses of gusacitinib had a 69.5% reduction in target lesion symptom score (TLSS), as compared with 49% among patients randomized to the lower dose of the drug, and 33.5% of placebo-treated patients. Response to gusacitinib occurred as early as 2 weeks after the start of treatment.
The higher dose of the JAK inhibitor led to a 72% improvement in the Hand Eczema Severity Index (HECSI) at 16 weeks, as compared with 20.8% in the placebo arm, reported Howard Sofen, MD, of Dermatology Research Associates and the University of California Los Angeles, at the American Academy of Dermatology virtual meeting.
The Society of Asian American Scientists in Cancer Research April 11 announced that it has honored 10 Indian American scientists for their outstanding cancer research.
Dr. Rajvir Dahiya, professor emeritus at U.C. San Franciscoâs School of Medicine and president of SAASCR, presented awards to these scientists April 11 during the American Association for Cancer Research annual meeting, according to the news release.
The awardees were Drs. Zaver M. Bhujwalla, Pankaj K. Singh, Neil Bhowmick, Anand Srivastava, Neeraj Saxena, Kaustubh Datta, Bhagavatula Moorthy, Nagi Kumar, Parameswaran Hari and Arun Sreekumar.
Bhujwalla is the William R. Brody Professor in the Russell H. Morgan Department of Radiology and Radiological Science of the Johns Hopkins University School of Medicine.
Living in the material world, ethically amid a pandemic theglobeandmail.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from theglobeandmail.com Daily Mail and Mail on Sunday newspapers.