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Breakthrough CU Anschutz research: First human trial of CAR-T cells manufactured on campus

Breakthrough CU Anschutz research: First human trial of CAR-T cells manufactured on campus
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

A Blip, Not A Surge: How Colorado Dodged A Holiday Coronavirus Tsunami

The drink that drives down your fat-triggering hormone

The drink that drives down your fat-triggering hormone Many of us have just made another resolution to lose the extra weight around our hips, thighs and belly. And more likely than not, we’ll give it up again in defeat. Not to sound glib, but if you want to really lose the weight, just drink more water but not for reason you think. And if you do, this year could be different! Why? Because thanks to researchers at the University of Colorado Anschutz Medical Campus we now know that losing weight could be as easy as drinking a glass of water.

CU Anschutz COVIDome Project aimed at speeding lifesaving treatment

Date Time CU Anschutz COVIDome Project aimed at speeding lifesaving treatment Researchers from across campus join in creation of online portal to serve as an open science ‘path to discovery’ Last spring, as healthcare providers and scientists around the world scrambled to treat a surge of patients infected with a virus that experts knew little about, one thing quickly became clear: SARS-CoV-2 strikes people differently. Faced with solving a mega-puzzle on a timer when minutes cost lives, clinical practice early in the pandemic became a fervent game of trial and error. Now, on the University of Colorado Anschutz Medical Campus, where the then-new Vice Chancellor for Research Thomas Flaig, MD, had the fortitude and resources to create a biobank of samples from some of the state’s first COVID-19 patients, a promising venture has sprung.

Inhaled Therapy Disrupts Excess Mucus Production in Allergic Asthma Model

Inhaled Therapy Disrupts Excess Mucus Production in Allergic Asthma Model Source: Sasha Suzi/Getty Images January 13, 2021 Share Nature Communications, the scientists explained how they created an inhaled treatment that disrupted the production of excess mucus by reducing disulfide bonds in mice and opening up their airways. The same treatment had similar impacts on human mucus samples. “Current asthma treatments have minimal effects on mucus, and the lack of therapeutic options stems from a poor understanding of mucus function and dysfunction at a molecular level and in vivo. Biophysical properties of mucus are controlled by mucin glycoproteins that polymerize covalently via disulfide bonds. Once secreted, mucin glycopolymers can aggregate, form plugs, and block airflow,” write the investigators.

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