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Pfizer, Moderna vaccines may be less effective against B1351 variant

Pfizer Shot Elicits Fewer Antibodies to South Africa Strain

Pfizer Shot Elicits Fewer Antibodies to South Africa Strain Bloomberg 2/18/2021 Naomi Kresge and Robert Langreth © Photographer: Michael Ciaglo/Getty Images Pharmacy technicians prepare doses of the Pfizer-BioNTech vaccine at a mass COVID-19 vaccination event on January 30, 2021 in Denver, Colorado. (Bloomberg) Pfizer Inc. and BioNTech SE’s Covid-19 vaccine stimulated roughly two-thirds lower levels of neutralizing antibodies against the South African variant of the coronavirus in a lab study. The Pfizer results are part of tests of its vaccine against a lab-created virus that had all the mutations found in the South African variant, which is thought to spread faster than earlier versions. The study released Wednesday showed reduced neutralization of the South Africa-like virus by blood from people who had been immunized with the Pfizer-BioNTech vaccine. The companies expect their vaccine will still work against the variant.

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