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MINNEAPOLIS - People with enlarged fluid-filled spaces in the brain around small blood vessels may be more likely to develop cognitive problems and dementia over time than people without these enlarged spaces, according to a new study published in the January 27, 2021, online issue of
Neurology®, the medical journal of the American Academy of Neurology.
Perivascular spaces are involved in clearing waste and toxins from the brain and may be associated with the brain changes associated with aging.
The study involved 414 people with an average age of 80. Participants took cognitive tests of thinking and memory skills and were assessed for the presence of dementia at the beginning of the study and every two years for eight years. The participants had MRI brain scans to check for enlarged perivascular spaces in two key areas of the brain at the start of the study and then every two years for eight years. The top quarter of the people with the largest number of enlarged per
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Enlarged fluid-filled spaces around cerebral small blood vessels were linked to cognitive decline, a prospective study of older adults showed.
Severe perivascular space pathology in both the basal ganglia and the centrum semiovale, or in the centrum semiovale alone, was tied to a greater drop in global cognition over 4 years, reported Matthew Paradise, MBChB, MSc, of the University of New South Wales in Sydney, Australia, and co-authors.
Large perivascular space dilation in both brain regions was an independent predictor of dementia across 8 years of follow-up (adjusted OR 2.91, 95% CI 1.43-5.95,
P=0.003), with stronger effects at either year 4 or 6, the researchers wrote in
Rachel Griffiths meets her desert Waterloo
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Hotel quarantine is no oneâs idea of fun, but the Northern Territoryâs Howard Springs quarantine facility recently provided a joyous life-enhancing visit for actor
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The actor and producer lived in a âdongaâ (local vernacular for a container house) last November at the disused workers camp 25 kilometres from central Darwin while en route from Melbourne to Queensland for a personal trip.
Quarantine at Howard Springs for Rachel Griffiths (right) and Rita Arrigo.
Credit:@ritaarrigo/Instagram
An early highlight included residents staging a spontaneous 45-minute water aerobics class after receiving negative COVID tests, with everyone singing âin quarantineâ to Abbaâs
3D Printing Bone-Like Structures that Contain Living Cells
Image Credit: University of New South Wales
A novel technique could lead to 3D printed bones that provide a more natural and less intrusive alternative to bone grafts.
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