The findings, published in
Science Immunology, suggest only a single vaccine dose may be needed to produce a sufficient antibody response.
Researchers found that those who did not have COVID-19 called COVID naïve did not have a full immune response until after receiving their second vaccine dose, reinforcing the importance of completing the two recommended doses for achieving strong levels of immunity.
The study provides more insight on the underlying immunobiology of mRNA vaccines, which could help shape future vaccine strategies.
“These results are encouraging for both short- and long-term vaccine efficacy, and this adds to our understanding of the mRNA vaccine immune response through the analysis of memory B cells,” says senior author E. John Wherry, chair of the department of systems pharmacology and translational therapeutics at the University of Pennsylvania and director of the Penn Institute of Immunology in the Perelman School of Medicine.
By Sola Ogundipe
Those who have had COVID-19 may only need one vaccine dose, a new study suggests People who have recovered from COVID-19 had a robust antibody response after the first mRNA vaccine dose, but a little immune benefit after the second dose, according to new research from the Penn Institute of Immunology.
The findings, published in Science Immunology, suggest only a single vaccine dose may be needed to produce a sufficient antibody response.
The team found that those who did not have COVID-19 called COVID naïve did not have a full immune response until after receiving their second vaccine dose, reinforcing the importance of completing the two recommended doses for achieving strong levels of immunity.
Study suggests persons who recover from COVID-19 may need one vaccine dose
On
By Sola Ogundipe
Those who have had COVID-19 may only need one vaccine dose, a new study suggests People who have recovered from COVID-19 had a robust antibody response after the first mRNA vaccine dose, but a little immune benefit after the second dose, according to new research from the Penn Institute of Immunology.
The findings, published in Science Immunology, suggest only a single vaccine dose may be needed to produce a sufficient antibody response.
The team found that those who did not have COVID-19 called COVID naïve did not have a full immune response until after receiving their second vaccine dose, reinforcing the importance of completing the two recommended doses for achieving strong levels of immunity.
Study spots genetic mutations linked to rare heart disorder in pregnant women
By (0)
Researchers have identified genetic mutations linked with a rare heart disorder in pregnant women, adding some explanation for why younger women develop a condition more typical of middle age. Photo by Free-Photos/Pixabay
April 20 (UPI) Genetics may explain why some younger women develop a heart ailment during pregnancy that is more typically found in middle-aged adults, according to a study published Tuesday by the journal Circulation.
Researchers at the University of Pennsylvania Perelman School of Medicine identified four genetic mutations that appear to put some otherwise healthy pregnant women at higher risk for peripartum cardiomyopathy, or weakness of the heart muscle.
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