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KANSAS CITY, MO One of the evolutionary disadvantages for mammals, relative to other vertebrates like fish and chickens, is the inability to regenerate sensory hair cells. The inner hair cells in our ears are responsible for transforming sound vibrations and gravitational forces into electrical signals, which we need to detect sound and maintain balance and spatial orientation. Certain insults, such as exposure to noise, antibiotics, or age, cause inner ear hair cells to die off, which leads to hearing loss and vestibular defects, a condition reported by 15% of the US adult population. In addition, the ion composition of the fluid surrounding the hair cells needs to be tightly controlled, otherwise hair cell function is compromised as observed in Ménière s disease.
Fight-or-Flight Protein Finding May Lead to New Treatments for Skeletal Muscle Disorders
April 26, 2021
Source: Skeletal Muscle Fibers (Cells) showing Striations, Teased apart 100X. Shows: 6 skeletal muscle fibers (cells), striations and multinucleate cells. [Ed Reschke/Getty Images]
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Scientists at the University of Cincinnati and colleagues report that a regulatory protein found in skeletal muscle fiber may play an important role in the body’s fight or flight response when encountering stressful situations.
The protein, fast skeletal myosin binding protein-C (fMyBP-C), plays a foundational role in the proper regulation of contractile structure and function in the body’s fast-twitch muscles, which produce sudden bursts of power to sprint into action, jump or lift heavy objects. Fast skeletal myosin binding protein-C modulates the speed and force of fast skeletal muscle contraction.
Regulatory protein in skeletal muscle fiber may play a key role in the body s fight or flight response
Researchers at the University of Cincinnati say a regulatory protein found in skeletal muscle fiber may play an important role in the body s fight or flight response when encountering stressful situations.
The protein, fast skeletal myosin binding protein-C (fMyBP-C), plays a foundational role in the proper regulation of contractile structure and function in the body s fast twitch muscles these muscles produce sudden bursts of power to sprint into action, jump or lift heavy objects. Fast skeletal myosin binding protein-C modulates the speed and force of fast skeletal muscle contraction.
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