University of Minnesota
A groundbreaking study led by engineering and medical researchers at the University of Minnesota Twin Cities shows how engineered immune cells used in new cancer therapies can overcome physical barriers to allow a patient’s own immune system to fight tumors. The research could improve cancer therapies in the future for millions of people worldwide.
The research is published in Nature Communications, a peer-reviewed, open access, scientific journal published by Nature Research.
Instead of using chemicals or radiation, immunotherapy is a type of cancer treatment that helps the patient’s immune system fight cancer. T cells are a type of white blood cell that are of key importance to the immune system. Cytotoxic T cells are like soldiers who search out and destroy the targeted invader cells.
Researchers from the University of Minnesota compared more than five years of data on the effects of three different dietary modifications prior to FDG-PET/CT scans in patients suspected of cardiac sarcoidosis. They found that a 72-hour daytime ketogenic diet resulted in increased myocardium suppression and diagnosis rates. Two of these dietary modification strategies are mainly applied and recommended by current guidelines and the third one, which performs better, has not been used in the clinical setting despite preclinical evidence to support its use, stated radiologist Dr. Can Ozutemiz, who led the study.
Cardiac sarcoidosis is a rare disease characterized by the formulation of granulomas in the tissue of the heart, and it can cause arrhythmias and heart failure. FDG-PET/CT has emerged as a promising alternative to invasive biopsies for diagnosing the condition, yet for physicians to be able to differentiate between normal physiologic myocardial activity and abnormal myocard
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MINNEAPOLIS, March 16, 2021 /PRNewswire/ Children s Cancer Research Fund (CCRF) is proud to award $10.5 million in its latest round of funding. The new grants support 12 research organizations that are working to improve treatment and outcomes for children and adolescents with cancer.
The grants fuel research in a few key areas of need, including the development of new therapies for some of the hardest to treat cancers like acute myeloid leukemia, sarcomas and relapsed liver cancer, as well as support of exceptional investigators and physicians still early in their careers. In addition, funds will enable three organizations to address a major barrier in pediatric cancer research the lack of cohesive, complete data sets readily accessible to all researchers. Solving this issue will support collaboration and be key to finding cures for these rare diseases.
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