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The link between fluoroquinolone antibiotics and aortic aneurysm (AA) was further strengthened by analysis of a U.S. commercial claims database.
Incidence of AA formation or dissection reached 7.5 per 10,000 prescription fills for fluoroquinolones at 90 days compared with 4.6 per 10,000 fills for comparator antibiotics (HR 1.20, 95% CI 1.17-1.24), according to Melina Kibbe, MD, and colleagues of the University of North Carolina at Chapel Hill. The study was published online in
JAMA Surgery, where Kibbe is an editor.
Patients filling prescriptions for these medications were also more likely to undergo aneurysm repair (HR 1.88 vs other antibiotics, 95% CI 1.44-2.46).
The study suggests fluoroquinolone use should be pursued with caution in all adults, not just in high-risk individuals as recommended by the current FDA black box warning, Kibbe s group wrote.
The initial early application deadline for campuses including the University of North Carolina at Chapel Hill and Georgia Institute of Technology came and went yesterday, and hundreds of students missed it.
Not because they were procrastinating (at least, not on Monday night), but because system-crashing technical glitches in the online Common Application continued to plague students (and their parents) who’ve been struggling to apply to college.
The issues stem from a system relaunch that took place and first caused technical problems in August. As the Oct. 15 deadline approached, some applicants paid the fee, then didn’t get a submit button (then paid a second time, only to have the same problem). Others made it all the way to the “print preview” stage, then got the spinning wheel of death. Others had full portions of essays deleted or couldn t submit documents. Still others couldn’t even log on to the system.
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A new study reveals that roughly one out of three large American rivers have appeared to change color since 1984, with many of the bodies of water seeming to slowly turn yellow and green and scientists tell Salon that this could mean some very bad things for human health.
Analyzing approximately 15.9 million satellite images taken over a period of more than three decades, researchers at the University of North Carolina at Chapel Hill, the University of Pittsburgh and Colorado State University discovered that of the more than 108,000 kilometers (roughly 67,000 miles) of rivers at least 60 meters (197 feet) wide studied throughout the country, 56% appeared predominantly yellow and 38% appeared predominantly green. While rivers often change color based on the seasons and flow regimes, the scientists found that one-third of rivers had experienced long-term significant color shifts between 1984 and 2018. (If you want to see what has happened with your local river, there
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Partial lockdowns could lead to an explosion in coronavirus cases, according to a top German researcher.
That is because the more people are in fewer places in less time, the more likely they are to pass on the virus, said Prof. Andrei Sommer, a visiting professor at Isra University in Jordan and formerly of the University of Ulm, in an interview with
The Jerusalem Post.
He compared the results of partial lockdowns to a nuclear explosion.
The immense destructive power of atomic weapons is the result of a sudden release of energy produced by splitting the nuclei of the fissile elements making up the bombs core, according to the Atomic Heritage Foundation in an article about the science behind the atomic bomb. In order to detonate an atomic weapon, you need a critical mass of fissionable material. The more you have, the greater the odds that an explosion will occur.