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SARS-CoV-2 spike protein can get into the brain

The coronavirus’ spike protein, often depicted as the red arms of the virus, can cross the blood-brain barrier in mice, researchers have found. More and more evidence is coming out that people with COVID-19 are suffering from cognitive effects, such as brain fog and fatigue. The new finding strongly suggests that SARS-CoV-2, the cause of COVID-19, can enter the brain. The spike protein, often called the S1 protein, dictates which cells the virus can enter. Usually, the virus does the same thing as its binding protein, says lead author William A. Banks, a professor of medicine at the University of Washington School of Medicine and a Puget Sound Veterans Affairs Healthcare System physician and researcher. Banks says binding proteins like S1 usually by themselves cause damage as they detach from the virus and cause inflammation.

COVID-19: This American County Has More Cases Than Canada

COVID-19: This American County Has More Cases Than Canada Douglas A. McIntyre © Provided by 24/7 Wall St. As the spread of COVID-19 across America has accelerated, the case count in California has ballooned at a terrible rate. The state has 1,827,535 of the U.S. total of 17,702,516 confirmed cases. California has 22,509 of America s 318,499 fatal cases. And California s COVID-19 figures are highest in Los Angeles County, the nation s largest by population. It has 596,910 confirmed cases and 8,757 deaths. The confirmed case count is higher than Canada s. Canada currently has 501,594 confirmed cases and 14,154 deaths. Its population is much larger than that of Los Angeles County. Canada has 37.6 million residents, while Los Angeles County has about 10 million. Obviously, the Los Angeles County cases are highly concentrated, based on geographic area, a factor that almost certainly must make the risk of spread higher.

SARS-CoV-2 s Spike Protein Can Enter the Brain in Mice

SARS-CoV-2’s Spike Protein Can Enter the Brain in Mice December 21, 2020 The COVID-19 symptoms on the center stage are those associated with pneumonia and respiratory distress. But there are also a host of symptoms that relate to the central nervous system. Although it is unclear whether or not the SARS-CoV-2 virus can enter the brain, a new study found that the spike protein can cross the blood–brain barrier (BBB) in mice, strongly suggesting that it can. The research is published in Coronaviruses, including the closely related SARS virus that caused the 2003–2004 outbreak, have been reported to be able to cross the BBB.

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