We re beginning to emerge from a pandemic-induced hibernation of sorts; the sun is shining and temperatures have warmed.
It s time to wake up and get .
Ultrasound, MRI Aid Placenta Accreta Diagnosis
Placental bulge sign on prenatal ultrasound or MRI helps diagnose severe placental accreta spectrum disorder warranting hysterectomy rather than conservative management
A) Ultrasound in 28-year-old woman (B) MRI in 34-year-old woman with suspected PAS disorder. Focal area of placental tissues bulge toward imaginary lines of normal uterine contour (dash lines). Length (L) and depth (D) measurements of placental bulge also demonstrated. p = placenta; b = bladder. Image courtesy of American Roentgen Ray Society (ARRS), American Journal of Roentgenology (AJR)
June 1, 2021 According to an open-access Editor s Choice article in ARRS
American Journal of Roentgenology (AJR), accurate prenatal diagnosis of severe placental accreta spectrum (PAS) disorder by imaging could help guide maternal counseling and selection between hysterectomy and uterine-preserving surgery.
Will quadruplet therapy become the standard induction therapy for newly diagnosed multiple myeloma?
Currently, standard induction therapy in the U.S. for the disease is a triple therapy of lenalidomide (Revlimid), bortezomib (Velcade), and dexamethasone (RVd), followed by stem cell transplantation in eligible patients and maintenance therapy with either lenalidomide or bortezomib.
Investigators are now evaluating how the addition of daratumumab (Darzalex), a monoclonal antibody targeting CD38, to triplet therapy can improve outcomes for patients with newly diagnosed myeloma. We want regimens that produce the longest disease-free or progression-free survival, because they predict the best outcomes, including long-term survival, said Rafael Fonseca, MD, chair of the Department of Internal Medicine at the Mayo Clinic in Phoenix. And you do that by achieving the deepest response possible, so getting the deepest response is the most important thing for a frontline regimen at the mom