UW–Madison tool aids in equitable vaccine distribution
The demand for COVID-19 vaccines continues to outpace supply, forcing public health officials to decide who should be first in line for a shot, even among those in the same pool of eligible vaccine recipients.
To assist these efforts, researchers at the University of Wisconsin School of Medicine and Public Health and UW Health have developed a tool that incorporates a person s age and socioeconomic status to prioritize vaccine distribution among people who otherwise share similar risks due to their jobs. The tool helps identify those who are at greater risk of severe complications or death from COVID-19.
UW researchers develop tool to equitably distribute limited vaccines For news media
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Nurse Nicole Metko, right, vaccinates nursing student Allison Chang with the first of a two-dose shot of the Moderna COVID-19 vaccine. Photo: Jeff Miller
The demand for COVID-19 vaccines continues to outpace supply, forcing public health officials to decide who should be first in line for a shot, even among those in the same pool of eligible vaccine recipients.
To assist these efforts, researchers at the University of Wisconsin School of Medicine and Public Health and UW Health have developed a tool that incorporates a person’s age and socioeconomic status to prioritize vaccine distribution among people who otherwise share similar risks due to their jobs. The tool helps identify those who are at greater risk of severe complications or death from COVID-19.
18) and quality trimmed by using Trimmomatic version 0.36 (
19). Viral contigs were generated by using default settings with Vicuna version 1.1 (
20), and a de novo consensus assembly was generated by using Viral Finishing and Annotation Toolkit (V-FAT) version 1.1 (https://www.broadinstitute.org/viral-genomics/v-fat). Read data are available from the National Center for Biotechnology Information Read Archive (https://www.ncbi.nlm.nih.gov) under BioProject accession no. PRJNA661611.
Phylogenetic Reconstruction
21) and IQ-TREE version 1.6 (
22). We then constructed a maximum-likelihood phylogenetic tree with 1,000 ultrafast bootstrap replicates (
HCV Transmission Network Analyses
We uploaded Illumina paired-end reads to GHOST and subjected them to automatic quality control criteria. In brief, read pairs were filtered out if a read had 3 Ns (N indicates that software was not able to make a basecall for this base) or a length 185 bp. Each identifier on forward and reverse reads
A new way to help the immune system fight back against cancer
January 8, 2021
Scientists at the University of Wisconsin School of Medicine and Public Health are breaking new ground to make cancer cells more susceptible to attack by the body’s own immune system.
Working in mice, a team led by Jamey Weichert, professor of radiology, and Zachary Morris, professor of human oncology, is combining two different techniques in its approach, using targeted radionuclide therapy, which delivers a low dose of cell-weakening radiation specifically to cancer cells, followed by immunotherapy, which helps the immune system to recognize and destroy cancer cells. The animal research is laying the foundation for future human and veterinary clinical trials.