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LSL60101 compound improves cognitive deficit in murine models with Alzheimer’s The LSL60101 compound, a specific ligand of the I2-IR receptors in the brain, could shed light on the development of future strategies against Alzheimer s disease. This is stated in the recent studies by the Research Group on Medicinal Chemistry and Pharmacology of Neurodegenerative Diseases of the University of Barcelona, published in the journals European Journal of Medicinal Chemistry and British Journal Pharmacology. In studies carried out with mice, LSL60101 has improved the cognitive deficit and the biomarkers related to the disease in these animal models. These studies result from the collaboration of the research teams led by professors Carmen Escolano, from the Faculty of Pharmacy and Food Sciences and the Institute of Biomedicine of the UB (IBUB), and Mercè Pallàs, from the same Faculty and the Institute of Neurosciences (UBNeuro). Framed within a program in the CaixaImpulse program, th

United kingdomSantiago de compostelaComunidad autonoma de catalunaSergio rodrChristian griCarmen escolanoFoteinin vasilopoulouEmily hendersonRega institute for medical research belgiumInstitute of biomedicineResearch group on medicinal chemistryUniversity of santiago de compostelaFood sciencesAutonomous university of barcelonaUniversity of the basque countryUniversity of belgrade servia