Blood thinners help patients with moderate COVID, clinical trials find
Global clinical trials examining the potential of blood thinners to treat moderately ill COVID-19 patients have proven so successful that physicians should immediately start using them in standard care, some Canadian doctors say.
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Full doses of heparin improved outcomes and decreased the need for life support in moderately ill patients
The Canadian Press ·
Posted: Jan 22, 2021 4:20 PM ET | Last Updated: January 22
Giving full-dose blood thinners to critically ill ICU patients was harmful, but it seems to help patients moderately ill with COVID-19, researchers have found. ( Jeffrey Sauger/Bloomberg/Getty)
Stepping Up to the Big Issues
Radiologists have recently taken on the role of activists and are tackling pressing issues in healthcare, including breast density
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Fazila Seker, Ph.D.
Radiologists who have long been professionals in the metaphorical and literal back-rooms of healthcare have recently found themselves in the limelight. Whether as figures at the forefront of legislative and clinical changes, or educators in the public sphere, radiologists are shaking up medicine for the better by tackling some of the most pressing issues in healthcare.
Breast Density
Women whose breasts have relatively little fat and more connective and glandular tissue are at higher risk of getting breast cancer. In fact, having dense breasts are an even greater risk factor than having a family history of breast cancer although researchers are not certain exactly why that is true.
A single genetic test can identify the presence and cause of mismatch repair deficiency
Researchers have developed a new integrated genetic/epigenetic DNA-sequencing protocol known as MultiMMR that can identify the presence and cause of mismatch repair (MMR) deficiency in a single test from a small sample of DNA in colon, endometrial, and other cancers. This alternative to complex, multi-step testing workflows can also determine causes of MMR deficiency often missed by current clinical tests. Their results are presented in the
Journal of Molecular Diagnostics, published by Elsevier.
MMR genes monitor and repair errors that can occur in normal cell replication and recombination. In some inherited and acquired cancers, one or more of the MMR genes are deactivated. The impact of MultiMMR is broad. Tumors with MMR deficiency respond well to new cancer immunotherapies, explains lead investigator Trevor J. Pugh, PhD, Department of Medical Biophysics, University of Toronto; Princess M
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