E-Mail
IMAGE: A diagram that shows the interconnectedness of the thousands of salivary proteins originating from blood plasma, parotid glands, and submandibular and sublingual glands. The diagram is one of many tools. view more
Credit: National Institute of Dental and Craniofacial Research
BUFFALO, N.Y. - To improve the development of new saliva-based diagnostic tests and personalized medicine, the National Institute of Dental and Craniofacial Research (NIDCR) has supported the development of the Human Salivary Proteome Wiki, the first public platform that catalogs and curates data on each of the thousands of proteins within our saliva.
Detailed in an article published on Tuesday, May 25 in the
Researchers test the effects of growth molecules exuded by oral bacteria
The human body is filled with friendly bacteria. However, some of these microorganisms, such as
Veillonella parvula, maybe too nice.
These peaceful bacteria engage in a one-sided relationship with pathogen
Porphyromonas gingivalis, helping the germ multiply and cause gum disease, according to a new University at Buffalo-led study.
The research sought to understand how
P. gingivalis colonizes the mouth. The pathogen is unable to produce its own growth molecules until it achieves a large population in the oral microbiome (the community of microorganisms that live on and inside the body).
Veillonella parvula and a pathogen in the mouth may lead to gum disease, a new study shows.
Friendly bacteria fills the human body. However, some of these microorganisms, such as
Veillonella parvula, may be
Porphyromonas gingivalis, it helps the germ multiply and cause gum disease, the researchers report.
The researchers wanted to understand how
P. gingivalis colonizes the mouth. The pathogen is unable to produce its own growth molecules until it achieves a large population in the oral microbiome (the community of microorganisms that live on and inside the body).
The answer: It borrows growth molecules from
V. parvula, a common yet harmless bacteria in the mouth whose growth is not population dependent.