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Breast Cancer Prognosis No Better With Five Versus Two Years of Zoledronate

Breast Cancer Prognosis No Better With Five Versus Two Years of Zoledronate
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Tumor Cell Changes Related to BrCa Survival

email article Early patterns of circulating tumor cells (CTCs) from metastatic breast cancer correlated with treatment response and subsequent survival, according to a meta-analysis involving more than 4,000 patients. Patients with negative CTC blood tests at baseline and a month later had median overall survival (OS) of almost 4 years. That compared with median OS of about 18 months for patients with two positive tests. Mixed results (positive/negative or negative/positive) were associated with OS in the middle. Similar results emerged when stratified by cancer subtype, Wolfgang Janni, MD, PhD, of University Hospital Ulm in Germany, reported during the San Antonio Breast Cancer Symposium virtual meeting.

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