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email article Standard chemotherapy and high-dose chemotherapy plus autologous stem cell transplant (ASCT) led to similar disease control after first relapse of early-stage, favorable, classic Hodgkin lymphoma, pooled data from two clinical trials showed. After adjustment for confounding factors, second progression-free survival (PFS) did not differ significantly between patients treated with standard chemotherapy or ASCT (HR 0.70, 95% CI 0.3-1.6, P=0.39). Subgroup analyses showed that patients younger than 60 had numerically superior 2-year second PFS (94.0% vs 83.3%) and overall survival (OS, 97.2% vs 88.4%) with chemotherapy, Paul J. Bröckelmann, MD, of University Hospital Cologne in Germany, and co-authors reported in the Relapse mostly occurs more than 12 months after initial diagnosis and with stage I-II disease, they concluded. Physicians choice CTx [chemotherapy] . is frequently applied as second-line therapy and is associated with similar second PFS and OS,

Charles bankheadMichael crumpUniversity of torontoUniversity hospital colognePrincess margaret cancer centerMedpage todayClin oncolசார்லஸ் வங்கித் தலைமைக்கேல் நொறுக்குபல்கலைக்கழகம் ஆஃப் டொராண்டோபல்கலைக்கழகம் மருத்துவமனை கொலோன்ப்ரிந்ஸெஸ் மார்கரெட் புற்றுநோய் மையம்