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Uniklinik Köln: 22-Jährigem mit Corona geht es immer schlechter und schlechter
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Wie gefährlich ist Long-Covid? : Eine Kölner Ärztin und ein Betroffener erzählen
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„Finanzwirtschaftliche Risiken : NRW ist noch skeptisch gegenüber Kölner Klinikverbund
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PET imaging can enable accurate diagnosis of recurring brain metastases
For patients with brain metastases, amino acid positron emission tomography (PET) can provide valuable information about the effectiveness of state-of-the-art treatments.
When treatment monitoring with contrast-enhanced magnetic resonance imaging (MRI) is unclear, adding 18F-FET PET can help to accurately diagnose recurring brain metastases and reliably assess patient response. This research was published in The
Journal of Nuclear Medicine.
Newer treatment options for patients with brain metastases such as immune checkpoint inhibitors and targeted therapies are effective, but can cause a variety of side effects. As a result, imaging findings on contrast-enhanced MRI can be highly variable, and it can be difficult to tell whether a treatment is working.
PET Imaging Adds Valuable Information to Brain Metastasis Monitoring
After radiosurgery concurrent with nivolumab in 59-year-old patient with melanoma BM (patient 1; Supplemental Tables 3 and 5), F-18 FET PET at follow-up 12 weeks after treatment initiation (bottom row) shows significant decrease of metabolic activity (TBRmean, ?28%) compared with baseline (top row), although MRI changes were consistent with progression according to iRANO criteria. Reduction of metabolic activity was associated with stable clinical course over 10 mo. CE = contrast-enhanced. Image created by N. Galldiks et al., Research Center Juelich, Juelich, Germany.
May 5, 2021 For patients with brain metastases, amino acid positron emission tomography (PET) can provide valuable information about the effectiveness of state-of-the-art treatments. When treatment monitoring with contrast-enhanced magnetic resonance imaging (MRI) is unclear, adding 18F-FET PET can help to accurately diagnose recurring brain meta