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Investegate |Telix Pharmaceuticals Limited Announcements | Telix Pharmaceuticals Limited: TLX66 Meets Study Objectives in Patients with AL Amyloidosis

World s first clinical trial on Covid-19 booster vaccines launched in UK

A study testing whether a booster vaccine dose could protect people against Covid and its variants has kicked off in the UK Close to 2 900 participants will be recruited, and seven different Covid vaccines will be tested as a third, booster dose Three of the seven vaccines will also be tested at half-dose  The UK has launched a world-first clinical trial in which volunteers will receive a third booster Covid-19 vaccine. The study will test seven Covid vaccines as a booster dose: Pfizer-BioNTech, Oxford-AstraZeneca, Moderna, Novavax, Janssen from Johnson & Johnson, Valneva, and CureVac. Researchers leading the study are hoping it will give them a better idea of the impact of a booster dose to protect people against Covid, as well as the protection it may offer against worrying variants.

Telix Pharmaceuticals Limited: TLX66 Meets Study Objectives in Patients with AL Amyloidosis

Telix Pharmaceuticals Limited: TLX66 Meets Study Objectives in Patients with AL Amyloidosis 9 Y-besilesomab) has met study objectives, demonstrating the initial safety profile in patients with Systemic Amyloid Light Chain Amyloidosis (AL amyloidosis). The TRALA trial ( AL Amyloidosis) is a Phase I/IIa trial to evaluate the safety and toxicity of TLX66 as the sole bone marrow conditioning agent prior to autologous hematopoietic stem cell transplantation (HSCT) in patients with AL amyloidosis. 1 The TRALA trial was sponsored by University Hospital Southampton in Southampton U.K. and run across four centres: Southampton, University College Hospital London, Royal Free Hospital London, and Queen Elizabeth Hospital Birmingham. All study data were reviewed by the trial s Independent Data Monitoring Committee (IDMC).

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