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Vitamin D deficiency does not increase risk of type 1 diabetes

Credit: Michele Blackwell on Unsplash, CC0 Genetically determined vitamin D levels do not have a large effect on risk of type 1 diabetes in Europeans, according to a study published 25th February 2021 in the open-access journal PLOS Medicine by Despoina Manousaki from the CHU Sainte Justine and the University of Montreal, Canada and colleagues. Type 1 diabetes is a relatively common autoimmune disease that inflicts substantial lifelong illness and significant economic burden. Its incidence is increasing worldwide, and there are no known interventions that can be used to prevent the disease. Vitamin D deficiency has been associated with type 1 diabetes in observational studies, but evidence of a causal effect from randomized controlled trials is lacking. In the new study, the researchers used a Mendelian randomization design to test whether genetically decreased vitamin D levels increase risk of type 1 diabetes. Mendelian randomization is a method of using measured variation in di

We have a legal and moral duty to clean up the air we breathe

Renewed funding for national childhood arthritis research centre

Date Time Renewed funding for national childhood arthritis research centre The UK’s first and only research centre dedicated to testing better and more effective drug treatments for children with arthritis and related conditions has secured a further three years of funding from the charity Versus Arthritis. The Experimental Arthritis Treatment Centre for Children (EATC4Children) is based in Liverpool at Alder Hey Children’s NHS Foundation Trust and the University of Liverpool. Since launching in 2014 the EATC4Children has led a wide range of studies including the landmark APTITUDE trial to improve treatment for children with the severe inflammatory eye condition uveitis, and a major programme of translational research into childhood lupus.

The NHS and care workers who have died during the pandemic

At least 246 frontline health and care workers have been identified after dying with coronavirus. Through tributes from loved ones and confirmation through sources such as local NHS trusts and other authorities, the PA news agency has confirmed the names of health and social care workers who have died after contracting Covid-19 since March 11 2020. This chronological list contains people who were working in roles shortly before their deaths where they were likely to come into contact with patients. The figure is likely to be lower than the true number of workers who have died, as the names of some victims will not yet be in the public domain.

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