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The Pew Charitable Trusts and the Alexander and Margaret Stewart Trust recently announced its 2021 class of the Pew-Stewart Scholars Program for Cancer Research, among them Indian American professor Ansuman Satpathy. Satpathy, of Stanford University, will investigate the genetic mechanisms of T-cell exhaustion, a phenomenon that arises with chronic immune stimulation during infections and cancers. The Satpathy lab will investigate the genetic mechanisms of T-cell exhaustion, a phenomenon that arises with chronic immune stimulation during infections and cancers. Cancer immunotherapies work by enhancing the ability of immune cells called T-cells to recognize and destroy tumor cells. However, this form of treatment is not effective in all patients or cancer types since the action of T-cells are not always sustained. To learn how T-cells become “exhausted,” his lab will employ a suite of genome-based technologies to map genetic changes in tumor-specific T-cells from over 100

United statesSusank urahnPeterm howleyAnsuman satpathyStanford cancer instituteMargaret stewartParker institute for cancer immunotherapyWashington university in stStanford universityPew stewart scholars program for cancer researchPew charitable trustsMargaret stewart trustPew stewart scholars programCancer researchIndian americanStanford university school