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A new observational trial has started, evaluating immune responses in patients with lymphoid cancers to COVID-19 vaccines.
The Prospective Observational Study Evaluating COVID-19 Vaccine Immune Responses in Lymphoid Cancer (PROSECO) trial aims to recruit 680 patients who will provide blood samples before and after vaccination so that clinicians can study their B and T cell responses.
Lymphoid cancers or lymphomas, originate from lymphocytes, a type of immune system cell. PROSECO is looking to recruit patient with all types of non-Hodgkin lymphoma, Hodgkin lymphoma, and chronic lymphocytic leukaemia.
The trial will run from seven sites across the UK – the centres in Southampton, Oxford, Nottingham, Leicester, Portsmouth, Norwich are now open and another is being set up in Newcastle. Patients with lymphoid cancer are being approached by clinicians and invited to attend but patients who live in areas of participating centres are encouraged to approach their clinicians if the
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For 18 hours a day, Andreas Greinacher and his team at Germany s Greifswald University Hospital have pored over blood samples from across Germany and Austria. Their mission: Trying to figure out how and why potentially deadly blood clots have appeared in a handful of patients who received AstraZeneca s coronavirus vaccine.
Matthias Schrader/AP
Potentially deadly blood clots have appeared in a handful of patients who received AstraZeneca s coronavirus vaccine, despite no link being established with the vaccine. No link has been established with the vaccine, widely used in Europe and other countries, including Canada and India, and under review for possible approval in the United States.