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IMAGE: Jennifer Gribble, a graduate student in the laboratory of Mark Denison, MD, at Vanderbilt University Medical Center. view more
Credit: Vanderbilt University Medical Center
Researchers at Vanderbilt University Medical Center (VUMC) and the University of Texas Medical Branch (UTMB) at Galveston have discovered what may be the Achilles heel of the coronavirus, a finding that may help close the door on COVID-19 and possibly head off future pandemics.
The coronavirus is an RNA virus that has, in its enzymatic toolkit, a proofreading exoribonuclease, called nsp14-ExoN, which can correct errors in the RNA sequence that occur during replication, when copies of the virus are generated.
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Vials of the Pfizer-BioNTech vaccine are prepared for distribution in Pinellas County on Dec. 16, 2020.
USF and Tampa General Hospital are helping run Phase 3 trials for a vaccine developed by Novavax. But it’s hard to get volunteers to take an experimental shot.
Just in time for the end of 2020, Coronavirus vaccines have arrived. The U.S. Food and Drug Administration has granted emergency approval to immunizations from Pfizer and Moderna. But work on other coronavirus vaccines continues.
On this week s episode of Florida Matters, it s all about the challenges of running a clinical trial during a pandemic.
The University of South Florida and Tampa General Hospital are helping to run clinical trials for a vaccine developed by pharmaceutical company Novavax. USF and TGH are looking to enroll 30,000 people in what is called a Phase 3 clinical trial.
Expert panel votes FDA SHOULD give Moderna s COVID-19 vaccine emergency approval amid hopes the U.S will soon have a second shot to help get 20 million Americans vaccinated by the end of 2020
A panel of FDA experts voted that the agency should approve Moderna s coronavirus vaccine and recommend whether the shot should be approved
With their endorsement, Moderna s shot will almost certainly get emergency approval tonight or tomorrow
Two people in Moderna s trial had severe allergic reactions: one who got a placebo, and a vaccine recipient who had anaphylactic shock 63 days later
Moderna determined neither were linked to the shot, and allergic reactions are generally immediate, not months later