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Spatiotemporal single-cell profiling reveals that invasive and tissue-resident memory donor CD8+ T cells drive gastrointestinal acute graft-versus-host disease

2Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. 3Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20858, USA. 4Fred Hutchinson Cancer Research Center, Department of Pediatrics, University of Washington, Seattle, WA 98109, USA. 5University of Washington, Seattle, WA 98195, USA. 6Washington National Primate Research Center, Seattle, WA 98195, USA. 7Division of Blood and Marrow Transplantation, Department of Pediatrics, Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55454, USA. 8Emory University School of Medicine, Atlanta, GA 30322, USA. 9Division of Gastroenterology, Boston Children’s Hospital and Program in Immunology, Harvard Medical School, Boston, MA 02115, USA. 10Harvard Stem Cell Institute, Cambridge, MA 02138, USA.

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