Shares of drugmaker
Affimed (NASDAQ:AFMD) are up 19% at 2:06 p.m. EDT after the company disclosed positive data from an early-stage clinical trial of its innate cell engager AFM13 in patients with Hodgkin s lymphoma.
So what
The data release only included results from the first four patients in the study, but they were impressive nonetheless.
All four patients responded to the therapy, which included giving the patients immune cells called natural killer (NK) cells and AFM13 that attracts the NK cells to the tumor cells. Two patients had a complete response, while the other two had a partial response. Adding to the impressiveness, these patients had already failed between four and 14 different lines of therapy before being given the NK cells plus AFM13.
SOTIO to Present Preclinical Results Describing SOT102 as Treatment of Solid Tumors at the American Association of Cancer Research Annual Meeting
, a clinical stage immuno-oncology company owned by PPF Group,
today announced
American Association of Cancer Research Annual Meeting
. The presentation focuses on
treatment of CLDN18.2-expressing solid tumors.
SOT102 (earlier SO-N102) is a CLDN18.2 targeting antibody-drug conjugate based on a novel proprietary, highly-specific monoclonal antibody conjugated to a potent cytotoxic drug molecule exhibiting strong anti-tumor activity. SOT102 was studied in models of various CLDN18.2-positive solid tumors, mainly of gastric and pancreatic origin.
Poster Presentation details:
Title: SOT102, a novel CLDN18.2-targeting antibody-drug conjugate with strong anti-tumor effect in various solid tumors expressing low target levels
A
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