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Preliminary NICE no for Merck s Bavencio

Preliminary NICE no for Merck s Bavencio 6th May 2021 The National Institute for Health and Care Excellence (NICE) has issued a preliminary rejection of NHS funds for use of Merck Serono s Bavencio (avelumab) as maintenance treatment of locally advanced or metastatic urothelial cancer. Currently, there are no maintenance treatments routinely available for locally advanced or metastatic urothelial cancer that has responded to platinum-based chemotherapy. However, in an appraisal consultation document, NICE said while clinical trial evidence shows that Bavencio can delay disease progression and extend survival versus best supportive care, it is uncertain how long people in the NHS who would be eligible for avelumab actually live for.

Hopes of cancer cure as stunning new therapy trains immune system to hunt and destroy disease

Stunning therapy lands knock-out blow to cancer

While it sounds like the stuff of science fiction, a cancer treatment in which a patient’s own cells are engineered to hunt down and wipe out their disease and then linger in the body to stop the cancer returning is helping to save patients’ lives. The results of the treatment, known as CAR T-cell therapy, have been astonishing.  Patients who had exhausted all other options and been told they had just months to live have gone into remission. Others have even been cured by the one-off dose. In trials, all signs of cancer disappeared in more than 80 per cent of patients with acute lymphoblastic leukaemia the most common cancer in children after receiving CAR T-cells.

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