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BOSTON - Concerns about fertility often influence how young women with breast cancer approach treatment decisions and are a reason for forgoing or delaying hormone-blocking therapy, a new study by Dana-Farber Cancer Institute investigators shows.
The findings, published online today by the journal
Cancer, reinforce the need for physicians to talk with patients about their fertility-related priorities and address them in treatment plans, the study authors write. Such conversations are important not only at the start of treatment but during its entire course, as patients goals and preferences may change over time. Young women with breast cancer face unique challenges, including issues surrounding fertility, says the study s lead author Tal Sella, MD, of Dana-Farber. For many premenopausal women with hormone receptor-positive breast cancer, long-term endocrine therapy [which blocks hormones that feed the cancer s growth] may prevent patients from having children while
Gender-affirming hormone therapy linked to blood pressure changes in transgender people
Gender-affirming hormone therapy (GAHT) was associated with blood pressure changes in both transgender men and women, according to new research published today in
Hypertension, an American Heart Association journal.
Given the higher burden of heart attack, stroke and other cardiovascular conditions among transgender men and women, blood pressure screening and monitoring are important, especially after beginning hormone therapies.
Although doctors have prescribed gender-affirming hormone therapy to transgender men and women for more than 25 years, researchers and health care professionals know little about rates of hypertension and how the effects on blood pressure change over time. Previous research has shown that transgender men were almost five times as likely to report having a heart attack compared to cisgender women.
Federal panel recommends continued âpauseâ on J&J vaccine until rare blood clots better understood Doctors hope to resolve safety issues in week to 10 days
By Jonathan Saltzman Globe Staff,Updated April 14, 2021, 1 hour ago
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A health care worker prepared a dose of the Johnson & Johnson vaccine early this month.Mark Kauzlarich/Bloomberg
Beset with unanswered questions, a federal advisory committee agreed Wednesday that use of Johnson & Johnsonâs COVID-19 vaccine should not resume in the United States until they get more information about a possible link between the shot and rare but severe blood clots in women under 50.
Bernie Madoffâs death recalls a devastating period in Boston philanthropic circles
Many of Bostonâs most prominent institutions and charities had benefited from donations from local clients of the swindler.
By Anissa Gardizy Globe Staff,Updated April 14, 2021, 2 hours ago
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Doctors enter the Brigham and Women s Hospital Carl J. and Ruth Shapiro Cardiovascular Center in Boston.NEAL HAMBERG
Bernie Madoffâs death in a federal prison on Wednesday likely conjured up unhappy memories for members of Bostonâs philanthropic sector who more than a decade ago were fleeced by the former investor, who ran a massive Ponzi scheme.
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