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The 3Rs of the genome: Reading, writing, and regulating

 E-Mail IMAGE: Researchers have precisely mapped the binding locations of over 400 proteins on the yeast genome using ChIP-exo. The method (top) uses an antibody to fish out a specific DNA-bound protein. view more  Credit: Pugh Lab, Cornell and Mahony Lab, Penn State A massive effort to map the precise binding locations of over 400 different kinds of proteins on the yeast genome has produced the most thorough and high-resolution map of chromosome architecture and gene regulation to date. The study reveals two distinct gene regulatory architectures, expanding the traditional model of gene regulation. So-called constitutive genes, those that perform basic housekeeping functions and are nearly always active at low levels require only a basic set of regulatory controls; whereas those that that are activated by environmental signals, known as inducible genes, have a more specialized architecture. This finding in yeast could open the door to a better understanding of the

Yeast epigenome map reveals details of gene regulation

A new Penn State and Cornell study describes an effort to produce the most comprehensive and high-resolution map yet of chromosome architecture and gene regulation in yeast.

Facebook Can Actually Boost Older Adults Well-Being - The Good Men Project

Facebook Can Actually Boost Older Adults’ Well-Being What older adults actually do on Facebook may be more important to their user experience and well-being than their overall use of the site, according to researchers.   A new study shows older adults experience different levels of competence, relatedness, and autonomy on Facebook based on the types of their activity. Specifically, older adults who posted more pictures to Facebook felt more competent, which led to significantly higher levels of well-being in general, according to researchers who report their findings in Commenting more frequently and receiving more responses to posts also called message contingency tended to improve feelings of relatedness and connection with others on Facebook, the researchers say. Further, older adults who customized their profiles gave them more of a sense of autonomy while on the site.

For older adults, specific Facebook activities more important than overall use

Certain Facebook activities linked to feelings of competence, relatedness and autonomy Researchers report that while overall Facebook use may be linked to poor well-being in older adults, specific activities on the social media site such as uploading pictures may lead to better outcomes, including improved sense of well-being. Image: Thanos Pal on Unsplash For older adults, specific Facebook activities more important than overall use Matt Swayne January 26, 2021 UNIVERSITY PARK, Pa. The actions that older adults take on Facebook may be more important to their user experience and well-being than their overall use of the site, according to researchers. In a study conducted by a team that included researchers from Penn State, older adults experienced different levels of competence, relatedness and autonomy on Facebook based on the types of their activities on the site.

Facebook can actually boost older adults well-being

What older adults actually do on Facebook may be more important to their user experience and well-being than their overall use of the site, according to researchers. A new study shows older adults experience different levels of competence, relatedness, and autonomy on Facebook based on the types of their activity. Specifically, older adults who posted more pictures to Facebook felt more competent, which led to significantly higher levels of well-being in general, according to researchers who report their findings in Commenting more frequently and receiving more responses to posts also called message contingency tended to improve feelings of relatedness and connection with others on Facebook, the researchers say. Further, older adults who customized their profiles gave them more of a sense of autonomy while on the site.

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