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Penn Study Suggests Those Who Had COVID-19 May Only Need One Vaccine Dose

Date Time Penn Study Suggests Those Who Had COVID-19 May Only Need One Vaccine Dose PHILADELPHIA People who have recovered from COVID-19 had a robust antibody response after the first mRNA vaccine dose, but little immune benefit after the second dose, according to new research from the Penn Institute of Immunology. The findings, published today in Science Immunology, suggest only a single vaccine dose may be needed to produce a sufficient antibody response. The team found that those who did not have COVID-19 called COVID naïve did not have a full immune response until after receiving their second vaccine dose, reinforcing the importance of completing the two recommended doses for achieving strong levels of immunity.

CHOP-led Research Study Identifies Key Target in Treatment-Resistant Hemophilia A

Date Time CHOP-led Research Study Identifies Key Target in Treatment-Resistant Hemophilia A Researchers at Children’s Hospital of Philadelphia (CHOP) have identified a key target that may be responsible for treatment failure in about 30% of patients with hemophilia A. The target, known as B cell activating factor (BAFF), appears to promote antibodies against and inhibitors of the missing blood clotting factor that is given to these patients to control their bleeding episodes. The findings, published in the Journal of Clinical Investigation, raise the possibility of using anti-BAFF therapies, potentially in combination with immune tolerance therapies, to tame the immune response in some patients with severe hemophilia A.

Penn study suggests those who had COVID-19 may only need one vaccine dose

Penn study suggests those who had COVID-19 may only need one vaccine dose
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Protein Found to Control Drivers of Normal Growth and Cancer

Protein Found to Control Drivers of Normal Growth and Cancer News provided by Share this article Share this article NEW YORK, April 14, 2021 /PRNewswire/ Researchers have found a long-sought enzyme that prevents cancer by enabling the breakdown of proteins that drive cell growth, and that causes cancer when disabled. Publishing online in Nature on April 14, the new study revolves around the ability of each human cell to divide in two, with this process repeating itself until a single cell (the fertilized egg) becomes a body with trillions of cells. For each division, a cell must follow certain steps, most of which are promoted by proteins called cyclins.

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