Study: TMEM41B transmembrane protein is a critical factor for SARS-CoV-2 replication
A single protein that appears necessary for the COVID-19 virus to reproduce and spread to other cells is a potential weakness that could be targeted by future therapies.
The molecule, known as transmembrane protein 41 B (TMEM41B), is believed to help shape the fatty outer membrane that protects the virus genetic material while it replicates inside an infected cell and before it infects another.
The latest finding comes from a pair of studies led by researchers at NYU Grossman School of Medicine and NYU Langone Health s Perlmutter Cancer Center, and colleagues at Rockefeller University and elsewhere.
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