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Newly Engineered Bacterium can Produce Carminic Acid Written by AZoMApr 7 2021 A team of researchers from the Korea Advanced Institute of Science and Technology (KAIST) has designed a bacterium that can produce carminic acid a natural red colorant that is extensively used in cosmetics and food. A schematic biosynthetic pathway for the production of carminic acid from glucose. Biochemical reaction analysis and computer simulation-assisted enzyme engineering were employed to identify and improve the enzymes (DnrFP217K and GtCGTV93Q/Y193F) responsible for the latter two reactions. Image Credit: The Korea Advanced Institute of Science and Technology (KAIST). The researchers have demonstrated the entire biosynthesis of carminic acid from glucose in a newly designed

United statesSouth koreaDae jangDongsoo yangNational research foundationJournal of the american chemical societyGeneration collaborative labDepartment of chemicalNovo nordisk foundationKorea advanced institute of scienceMinistry of scienceKorea advanced instituteCanary islandsWoo dae jangDistinguished professor sang yup leeAmerican chemical society