Canadian pilot study uses gene therapy to successfully treat patients with Fabry disease
Results of a world-first Canadian pilot study on patients treated with gene therapy for Fabry disease show that the treatment is working and safe.
The Canadian research team was the first to use gene therapy in 2017 to treat patients with Fabry disease, a rare, chronic illness that can damage major organs and shorten lives. They report their findings today in the journal
Nature Communications. Being one of the first people in the world to receive this treatment, and seeing how much better I felt afterward, it definitely gives me hope that this can help many other Fabry patients and potentially those with other single gene mutation disorders, says Ryan Deveau, one of the participating patients in Dartmouth, Nova Scotia. Now that I don t have to get the replacement therapy every two weeks, I have more time to spend with my family.
Gene therapy show promise in taming rare disease: U of C scientist
calgaryherald.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from calgaryherald.com Daily Mail and Mail on Sunday newspapers.
A Canadian success story: world-first to treat Fabry disease with gene therapy
newswise.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from newswise.com Daily Mail and Mail on Sunday newspapers.
Credit: Dana-Farber Cancer Institute
In a major advance in the treatment of multiple myeloma, a CAR T-cell therapy has generated deep, sustained remissions in patients who had relapsed from several previous therapies, an international clinical trial has found.
In a study posted online today by the
New England Journal of Medicine, trial leaders report that almost 75% of the participants responded to the therapy, known as idecabtagene vicleucel (ide-cel), and one-third of them had a complete response, or disappearance of all signs of their cancer. These rates, and the duration of the responses, are significantly better than those produced by currently available therapies for patients with multiple relapses, according to investigators.
How will Ontario schools keep kids safe during the third wave?
With schools in the province reopened, many conflicted parents are wondering what improvements if any have been made. Aaron Hutchins
It was sometime in August 2020, before the
last reopening of schools in Ontario, that Sarah Liss became fixated with ventilation. Her older child goes to school in the Toronto District School Board, in the kind of building where students complain about the sweltering heat on warmer days. Only now she was worried about COVID.
With school boards and the province focusing on
masks, cohorting and cleaning, Liss used her spare time researching another vital factor identified by health and science experts for slowing transmission: ventilation. Specifically, she began looking for solutions to get air purifiers into classrooms not only across the city, but the entire province.