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Trauma patients with COVID-19 face greater risk of complications and death

 E-Mail PHILADELPHIA In addition to sickening and taking the lives of millions across the globe, COVID-19 complicated patient care in a range of less-direct ways, from increased incidence of heart attacks to decreased cancer screenings. The virus also increased the risk of complications and death among trauma patients with injuries from car crashes, falls or other accidents, or who were victims of violent injuries such as gunshots and stabbings, according to new research conducted by the Perelman School of Medicine at the University of Pennsylvania published recently in The findings reveal that patients in trauma centers across the state of Pennsylvania who also tested positive for COVID-19 had six times higher risk of death than patients with similar injuries without COVID. COVID-positive patients also demonstrated double the likelihood of complications such as venous thromboembolism, renal failure, need for intubation, and unplanned ICU admission, as well as more than five tim

COVID-19 patients with traumatic injuries have six times higher risk of complications, death

COVID-19 patients with traumatic injuries have six times higher risk of complications, death In addition to sickening and taking the lives of millions across the globe, COVID-19 complicated patient care in a range of less-direct ways, from increased incidence of heart attacks to decreased cancer screenings. The virus also increased the risk of complications and death among trauma patients with injuries from car crashes, falls or other accidents, or who were victims of violent injuries such as gunshots and stabbings, according to new research conducted by the Perelman School of Medicine at the University of Pennsylvania published recently in The Journal of Trauma and Acute Surgery.

The Discovery Labs Signs Foundational Lease with the University of Pennsylvania Gene Therapy Program as Anchor Tenant

Penn nursing-led Philly team awarded $1 4 million NIH grant to expand COVID-19 outreach

Credit: Penn Nursing PHILADELPHIA (May 19, 2021) - José A. Bauermeister, PhD, and Antonia M. Villarruel, PhD, are leading one of 10 new research teams from across the country that received National Institutes of Health (NIH) grants totaling $14 million to extend the reach of the NIH s Community Engagement Alliance (CEAL) Against COVID-19 Disparities. The Philly CEAL team was awarded $1.4 million from the NIH with additional support from Penn Nursing and The University of Pennsylvania, bringing the total for the alliance to $1.53 million. The toll of the pandemic among racial/ethnic populations in Philadelphia cannot be understated. Alongside the stark morbidity and mortality COVID-19 estimates reported by the city, racial/ethnic minorities in Philadelphia have also been most likely to experience job loss, income reduction, and decreased access to social resources, said Bauermeister, the Albert M. Greenfield Professor of Human Relations and Chair of the Department of Family & Co

Researchers use arcuate organoids to study development and disease of the hypothalamus

 E-Mail PHILADELPHIA Human brain organoids are remarkable platforms for modeling features of human brain development and diseases. Building on methods to generate organoids to model different brain regions such as the cortex and the midbrain, researchers at the Perelman School of Medicine at the University of Pennsylvania have generated the first organoids of the arcuate nucleus (ARC), an essential structure in the hypothalamus that sends signals of hunger and feeling full. This part of the hypothalamus exhibits a tremendous amount of cell diversity, and is far more complex than previously modeled parts of the brain. In a paper published today in

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