by Dr Jayashree on May 18, 2021 at 12:05 AM
Blood pressure is controlled by many medications but in some people, they don t work as desired resulting in drug resistant hypertension and so they need additional therapeutic approaches to help patients get their blood pressure under control.
To overcome this issue, recently a study led by researchers at Columbia University Vagelos College of Physicians and Surgeons and New York-Presbyterian published in journal
The Lancet tests a clinical procedure called Renal denervation , that delivers two to three short blasts of ultrasound to nerve fibres that travel close to the renal artery.
The participants of the study were adults with moderate to severe hypertension despite taking three or more antihypertensive drugs, among them 69 were treated with renal denervation and 67 had the sham procedure.
Brief pulses of ultrasound delivered to nerves near the kidney lowered blood pressure in people with drug-resistant hypertension, Columbia and NewYork-Presbyterian physicians have found.
May 16, 2021
Ultrasound-based renal denervation (Paradise; ReCor Medical) significantly lowers systolic blood pressure when compared with a sham procedure in patients with resistant hypertension treated on a background of antihypertensive therapy, the RADIANCE-HTN TRIO shows.
Renal denervation reduced daytime ambulatory systolic blood pressure by 8.0 mm Hg compared with a 3.0-mm Hg reduction observed in patients treated with the sham procedure, a median between-group difference of 4.5 mm Hg (
P = 0.02). Additionally, there were significant between-group reductions in 24-hour ambulatory systolic blood pressure, nighttime ambulatory systolic blood pressure, and office- and home-based systolic blood pressure.
“I don’t want to be perceived as overselling anything, but sham-controlled controls are great for determining if there is an effect or not,” senior investigator Ajay Kirtane, MD (NewYork-Presbyterian/Columbia University Irving Medical Center, New York, NY), told TCT
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