by Jason Anthony
The COVID-19 pandemic brought a vast mobilization of scientific ingenuity. At the same time, work on other medical threats continued to push forward. This week, Proto
looks at the most transformational non-COVID-19 research of 2020.
Any medication is, in one sense, a molecular shape. The prescribing physician is hoping that it will lock on to complementary shapes in the body and create a positive change. As the body’s own molecular shapes have come into greater focus over the past century, it has enabled researchers to create even more precise medications for a wider range of conditions. Two major breakthroughs on that front in 2020 the first time “seeing” an atom with cryogenic electron microscopy, and a new way to predict how a protein folds promises to dramatically help the drug development of tomorrow.
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