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UNSW researcher awarded $1.8m international life science grant
A UNSW Sydney researcher has received a prestigious international grant to study the origins of movement in bacteria and its application to present-day biology.
Dr Matthew Baker is the only Australian research lead to be awarded a 2021 Human Frontier Science Program Research Grant – Early Career. Photo: UNSW Sydney
Scientia Senior Lecturer Dr Matthew Baker has been awarded a 2021 Human Frontier Science Program (HFSP) Research Grant – Early Career, to experimentally recreate the emergence of bacterial motility and measure the evolutionary constraints which govern gain of function.
The HFSP is a world-leading funding body dedicated to supporting fundamental biological research and promoting intercontinental collaboration. Its research grants are designed to create new approaches for understanding the complex structures and regulatory networks of living organisms, their evolution and interactions. Research
2021 HFSP research grants
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2021 HFSP postdoctoral fellowships
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IMAGE: In this visualization of antibody target sites, the SARS-CoV-2 spike protein is tethered to the viral membrane with a slender stalk. Patches of intense purple color at the surface of. view more
Credit: Mateusz Sikora, Sören von Bülow, Florian E. C. Blanc, Michael Gecht, Roberto Covino and Gerhard Hummer
A new, detailed model of the surface of the SARS-CoV-2 spike protein reveals previously unknown vulnerabilities that could inform development of vaccines. Mateusz Sikora of the Max Planck Institute of Biophysics in Frankfurt, Germany, and colleagues present these findings in the open-access journal
PLOS Computational Biology.
SARS-CoV-2 is the virus responsible for the COVID-19 pandemic. A key feature of SARS-CoV-2 is its spike protein, which extends from its surface and enables it to target and infect human cells. Extensive research has resulted in detailed static models of the spike protein, but these models do not capture the flexibility of the sp
March 17, 2021
Breast cancer poses a substantial threat as it spreads to other organs, often lying in wait for years in these tissues and recurring without warning. Bones are a prime target, but the mechanisms that influence whether skeletal metastasis will develop or not remain poorly understood.
A collaboration between researchers at Cornell and the Max Planck Institute (MPI) of Colloids and Interfaces in Potsdam, Germany, used an innovative combination of biological and materials characterization tools to reveal that bones may actually grow in response to signals from a distant breast tumor – possibly as a preemptive defense mechanism against metastasis. The findings could point the way to future diagnostic tests and therapeutic treatments.