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Twenty years ago, the science journal Nature published the first draft of the human genome the sequence of chemical “letters” on the gene-bearing DNA of our chromosomes.
The Human Genome Project (HGP) had labored for a decade to read this coded information. In a White House press conference in 2000, Francis Collins, who led the project as director of the US National Human Genome Research Institute, waxed Biblical, calling the human genome “our own instruction book, previously known only to God.”
The HGP has huge potential benefits for medicine and our understanding of human diversity and origins, but a blizzard of
Twenty years ago, the science journal Nature published the first draft of the human genome: the sequence of chemical “letters” on the gene-bearing DNA of our chromosomes. The Human Genome Project (HGP) had laboured for a decade to read this coded information. In a White House press conference in 2000, Francis Collins, , who led the project as director of the US National Human Genome Research Institute, waxed biblical, calling the human genome.
Misleading rhetoric has fuelled the belief that our genetic code is an ‘instruction book’ – but it’s far more interesting than that
‘Successes in gene therapy remain rare, and medicine tailored to people’s individual genetic constitution has not yet materialised.’ Photograph: Alamy
‘Successes in gene therapy remain rare, and medicine tailored to people’s individual genetic constitution has not yet materialised.’ Photograph: Alamy
Wed 9 Jun 2021 06.43 EDT
Last modified on Wed 9 Jun 2021 06.45 EDT
Twenty years ago, the science journal Nature published the first draft of the human genome: the sequence of chemical “letters” on the gene-bearing DNA of our chromosomes. The Human Genome Project (HGP) had laboured for a decade to read this coded information. In a White House press conference in 2000, Francis Collins, , who led the project as director of the US National Human Genome Research Institute, waxed biblical, calling the human genome “our own instructio
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Along with the pneumonia, blood clots, and other serious health concerns caused by SARS-CoV-2, the COVID-19 virus, some studies have also identified another troubling connection. Some people can develop diabetes after an acute COVID-19 infection.
What’s going on? Two new NIH-supported studies, now available as pre-proofs in the journal
Cell Metabolism [1,2], help to answer this important question, confirming that SARS-CoV-2 can target and impair the body’s insulin-producing cells.
Type 1 diabetes occurs when beta cells in the pancreas don’t secrete enough insulin to allow the body to metabolize food optimally after a meal. As a result of this insulin insufficiency, blood glucose levels go up, the hallmark of diabetes.