Commonly prescribed cholesterol-lowering drugs could be effective in treating ulcerative colitis news-medical.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from news-medical.net Daily Mail and Mail on Sunday newspapers.
Nanotech Jumps Blood-Brain Barrier To Kill Cancer in Mice
A new synthetic protein nanoparticle capable of slipping past the nearly impermeable blood-brain barrier in mice could deliver cancer-killing drugs directly to malignant brain tumors, new research shows.
The study is the first to demonstrate an intravenous medication that can cross the blood-brain barrier.
I’ve worked in this field for more than 10 years and have not seen anything like this.
The discovery could one day allow new clinical therapies for treating glioblastoma, the most common and aggressive form of brain cancer in adults, and one whose incidence is rising in many countries. Today’s median survival for patients with glioblastoma is around 18 months; the average 5-year survival rate is below 5%.
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Atherosclerosis is marked by the buildup of inflammatory cells which narrow arteries to the point of chest pain and muscle weakness. Severe cases result in lesions and internal ruptures of arteries or even thrombosis in coronary arteries. One way that investigators are working to understand how atherosclerosis occurs and progresses is by looking at long non-coding RNAs (lncRNAs), strands of RNA that are not translated into proteins and which may play integral but understudied roles in cell regulation and disease progression. Through utilization of genetically modified high-risk atherosclerotic mice, a research team from Brigham and Women s Hospital identified and characterized Macrophage-Associated Atherosclerosis lncRNA Sequence (MAARS), which is expressed specifically in macrophages in atherosclerotic plaques and contributes to the progression of the disease. Results are published in
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RYE BROOK, N.Y., Dec. 14, 2020 /PRNewswire/ As the world confronts a viral pandemic not seen in the past 100 years, the reverberations are being felt across every sector, from healthcare to the economy, education, business and science, including the blood cancer community. Blood cancers don t stop for the Covid-19 virus and the urgent need for collaboration to address these challenges has never been starker.
In response, The Leukemia & Lymphoma Society (LLS) today announced it has forged significant alliances with premier foundations, cancer institutions and philanthropic individuals, bringing their collective resources to bear to co-fund approximately $9 million in new research grants, with up to $8 million more funding anticipated over the next year. This cooperation will allow LLS to continue driving forward impactful research to find better treatments and cures for patients with leukemia, lymphoma, myeloma and other blood cancers.