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NK cells with bispecific antibody show activity against lymphoma cells

Date Time NK cells with bispecific antibody show activity against lymphoma cells Cytokine-activated natural killer (NK) cells derived from donated umbilical cord blood, combined with an investigational bispecific antibody targeting CD16a and CD30 known as AFM13, displayed potent anti-tumor activity against CD30+ lymphoma cells, according to a new preclinical study from researchers at The University of Texas MD Anderson Cancer Center. The findings were published today in Clinical Cancer Research, a journal of the American Association for Cancer Research. These results led to the launch of a Phase I clinical trial to evaluate the combination of cord blood-derived NK cells (cbNK cells) with AFM13 as an experimental cell-based immunotherapy in patients with CD30+ lymphoma.

United statesKaty rezvaniPinaki banerjeeAmerican association for cancer researchUniversity of texas md anderson cancer centerNational institute of healthNational cancer instituteMd anderson cord blood bankClinical cancer researchAmerican associationStem cell transplantationCord blood bankCancer researchNational instituteInstitutional conflictPinterest management

Affimed Announces Publication of Preclinical Data in Clinical Cancer Research Supporting Therapeutic Potential of AFM13 in Combination with Natural Killer Cells

Affimed Announces Publication of Preclinical Data in Clinical Cancer Research Supporting Therapeutic Potential of AFM13 in Combination with Natural Killer Cells
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Clinical cancer researchCancer cellsNatural killerPreclinical dataNk cellsClinical studyமருத்துவ புற்றுநோய் ஆராய்ச்சி

New Marker Predicts Benefit of Radiotherapy for Early-stage Breast Cancer

New Marker Predicts Benefit of Radiotherapy for Early-stage Breast Cancer May 11, 2021 A study involving researchers at Karolinska Institutet and Gothenburg University in Sweden has found that low levels of a protein called PDGFRb are associated with particularly good results of radiotherapy in women with early-stage breast cancer. The study, which is published in the journal Clinical Cancer Research, also suggests that the efficacy of radiotherapy can be improved with drugs that block this protein. Some 900 women in Sweden are diagnosed with DCIS (ductalcarcinoma in situ), the earliest possible form of invasive breast cancer. Standard treatment is surgery and subsequent radiotherapy. Although the prognosis is generally good, some ten per cent of patients suffer a recurrence within ten years of diagnosis.

Uppsala lanVastra gotalands lanKarolinska institutetCarina strellUppsala universityGothenburg universityDepartment of immunologyClinical cancer researchDepartment of oncologyClinical sciencesகோடெந்ப்ர்க் பல்கலைக்கழகம்துறை ஆஃப் நோயெதிர்ப்புமருத்துவ புற்றுநோய் ஆராய்ச்சிதுறை ஆஃப் புற்றுநோயியல்மருத்துவ அறிவியல்

Guardant Health Inc (GH) Q1 2021 Earnings Call Transcript

Operator Thank you for standing by, and welcome to the Guardant Health Q1 2021 Earnings Call. [Operator Instructions] It is now my pleasure to hand the conference over to Carrie Mendivil from Investor Relations. Carrie Mendivil Investor Relations Thank you. Earlier today, Guardant Health released financial results for the quarter ended March 31, 2021. If you have not received this news release or if you d like to be added to the company s distribution list, please send an email to investors@guardanthealth.com. Joining me today from Guardant is Helmy Eltoukhy, Chief Executive Officer; AmirAli Talasaz, President; and Mike Bell, Chief Financial Officer. Before we begin, I d like to remind you that management will make statements during this call that are forward-looking statements within the meaning of federal securities laws. These statements involve material risks and uncertainties that could cause actual results or events to materially differ from those anticipated. Additiona

United statesDan arias stifelAmirali talasazDan ariasDaiichi sankyoMike bellHelmy eltoukhyPuneet soudaCarrie mendivilMichael bellGuardant health incExchange commissionGuardant healthHospital cancer centerAffairs oncology for genentechClinical cancer research

Tech Talk: Mapping the galaxy s edge and using AI to treat cancer | Technically Speaking

Tech Talk: Mapping the galaxy s edge and using AI to treat cancer | Technically Speaking
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United statesUniversity of arizonaSteward observatoryChristopher williamsGurtina beslaHarvard universityUniversity of leedsClinical cancer researchUnited university of leedsMilky wayLarge magellanic cloudLarge magellanicUnited kingdom based universityTucson based roche tissueClinical cancerஒன்றுபட்டது மாநிலங்களில்