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PreludeDx™ Presents New Data at SABCS Spotlight Session Re-Classifying Patients Meeting RTOG 9804 Low Risk Criteria as Elevated Risk Using DCISionRT®

Share this article Share this article LAGUNA HILLS, Calif., Dec. 15, 2020 /PRNewswire/ Prelude Corporation (PreludeDxä), a leader in molecular diagnostics and precision medicine for early stage breast cancer, presented clinical outcomes data last week at the San Antonio Breast Cancer Symposium (SABCS) that further validates the DCISionRT® test results of an independent study by Kaiser Permanente Northwest published earlier this year in Clinical Cancer Research.  DCISionRT is a biologic risk signature that assess the 10-yr risk of a subsequent breast cancer recurrence.  A Spotlight Poster presented at SABCS, showed that the DCISionRT test reclassified 45% of patients meeting RTOG 9804 low risk or good risk criteria for Ductal Carcinoma In Situ (DCIS) as Decision Score (DS) Elevated Risk.  These patients who were reclassified by the DCISionRT test to DS Elevated Risk had clinically elevated 10-year breast cancer rates when treated without radiation therapy (RT) and demons

Collaboration Driving Progress: LLS Forms Alliances with Leading Cancer Institutions and Foundations to Co-Fund nearly $17 million in New Research Grants

Share this article Share this article RYE BROOK, N.Y., Dec. 14, 2020 /PRNewswire/  As the world confronts a viral pandemic not seen in the past 100 years, the reverberations are being felt across every sector, from healthcare to the economy, education, business and science, including the blood cancer community. Blood cancers don t stop for the Covid-19 virus and the urgent need for collaboration to address these challenges has never been starker. In response, The Leukemia & Lymphoma Society (LLS) today announced it has forged significant alliances with premier foundations, cancer institutions and philanthropic individuals, bringing their collective resources to bear to co-fund approximately $9 million in new research grants, with up to $8 million more funding anticipated over the next year. This cooperation will allow LLS to continue driving forward impactful research to find better treatments and cures for patients with leukemia, lymphoma, myeloma and other blood cancers.

A new model for assessing kidney function in cancer patients

Calibrating kidney function for cancer patients

 E-Mail IMAGE: To tame a tumor, clinicians must give a patient the right amount of drugs. Too little, and it will not destroy the tumor. Too much, and it could damage tissues. view more  Credit: Ben Wigler/CSHL, 2020 Cold Spring Harbor Laboratory (CSHL) scientists have developed a new model for assessing kidney function in cancer patients as part of an international collaboration that involved contributions from the United Kingdom and Sweden. The model gives clinicians a new tool to aid dose determinations for chemotherapy to treat a patient s disease while limiting the drugs harmful effects. Chemotherapy drugs are usually injected into the bloodstream and removed from the body as blood filters through the kidneys. Sometimes the drugs harm the kidneys. Understanding how efficiently a patient can filter blood is essential for predicting how the body will process a drug and monitoring treatment effects. To be sure a treatment reaches tumor cells at the right dose, patie

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