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Researchers use appendiceal cancer organoids to study personalized immunotherapy response Wake Forest researchers and clinicians are using patient-specific tumor organoid models as a preclinical companion platform to better evaluate immunotherapy treatment for appendiceal cancer, one of the rarest cancers affecting only 1 in 100,000 people. Immunotherapies, also known as biologic therapies, activate the body s own immune system to control, and eliminate cancer. Appendiceal cancer is historically resistant to systemic chemotherapy, and the effect of immunotherapy is essentially unknown because clinical trials are difficult to perform due to lack of adequate patient numbers, resulting in a lack of data and limited research models.

Shay sokerKonstantinosi votanopoulosEmily hendersonWake forest organoid research centerCancer centerWake forest institute for regenerative medicineWake forest comprehensive cancer centerClinical cancer researchWake forest instituteRegenerative medicineComprehensive cancer centerஎமிலி ஹென்டர்சன்புற்றுநோய் மையம்எழுந்திரு காடு நிறுவனம் க்கு மீளுருவாக்கம் மருந்துஎழுந்திரு காடு விரிவான புற்றுநோய் மையம்மருத்துவ புற்றுநோய் ஆராய்ச்சி