Reactive oxygen species are important components in cancer treatments
Reactive oxygen species (ROS) are highly reactive chemicals which contain oxygen radicals. Hypochlorous acid, peroxides, superoxide, singlet oxygen, alpha-oxygen and hydroxyl radicals are the major examples of ROS, which are familiar to persons from many walks of life as they are used in many domestic and industrial processes.
ROS are naturally produced during a variety of biochemical reactions within the cell organelles such as the endoplasmic reticulum, mitochondria and peroxisomes. ROS are also formed as a byproduct of the normal metabolism of oxygen.
The production of ROS can be induced by various factors such as heavy metals, tobacco, smoke, drugs, xenobiotics, pollutants and radiation. From various experimental studies, it is reported that ROS acts as either tumor suppressing or tumor promoting agent. The elevated level of ROS can arrest the growth of tumor through the persistent increase in cell cycle inh
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