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Study uncovers two phases of infection in patients with severe COVID-19 pneumonia BOSTON - What does SARS-CoV-2, the virus that causes COVID-19, do once it enters a person s airways, and how does infection in lung cells affect patients immune responses? New research led by investigators at Massachusetts General Hospital (MGH) and published in Nature Communications provides insights that could help improve treatment strategies for infected patients. To analyze SARS-CoV-2 at the tissue level, the scientists examined autopsied material from 24 patients who succumbed to COVID-19. We used a method called RNA in situ hybridization to visualize the actual SARS-CoV-2 virus in human lung specimens. This assay is now a clinical test being used at MGH to understand what tissues can be infected by the virus, explains co-author David T. Ting, MD, associate clinical director for Innovation at the Mass General Cancer Center and an assistant professor of Medicine at Harvard Medical School.

United statesMedicine at harvard medical schoolNature communicationsPershing square sohn prize mark foundationResearch scholars programNational institutes of healthCancer centerV foundationMassachusetts general hospitalMass general cancer centerHarvard medicalMass general cancerNational institutesScholars programஒன்றுபட்டது மாநிலங்களில்மருந்து இல் ஹார்வர்ட் மருத்துவ பள்ளி